News Things You Should Know About Fenbendazole

Things You Should Know About Fenbendazole


Often referred to as Fenben or Panacur, fenbendazole is a member of the benzimidazole class of anthelmintic medicines which has been employed across the world since its invention in 1974. Recent studies have uncovered that fenbendazole in addition to related drugs have shown a considerable anti-cancer effect.

Theories were proposed that the drug used for de-worming dogs could be repurposed as a cancer medication. Benzimidazole drugs may be similar to existing cancer drugs such as Taxol and vinca alkaloids. The available toxicity data suggests that fenbendazole is likely safe when orally ingested by humans, though there is a lack of specific studies involving humans.

Typically, untreated fenbendazole is typically sold in a powdered form and is usually white in color with poor water solubility.

This medication is not well reabsorbed in the intestines. Consuming food in the stomach may improve its bioavailability.

What is the function of fenbendazole?

Fenbendazole is meant to target parasites by hindering the formation of microtubules by connecting to β-tubulin. This blocks the combination of tubulin into pairs in the parasites’ cells, which eventually leads to their demise.

It appears that fenbendazole, along with other benzimidazoles, has a similar impact when used against cancer cells. Presently, three primary ways that fenbendazole is thought to eliminate cancer cells are believed to exist.

This medicine is believed to work against cancer by causing apoptosis, which is thought to involve the medicine’s interaction with β-tubulin which halts cell division and is toxic to the cell.

There is ample evidence that benzimidazole carbamates disrupt tubulin polymerization into microtubules in worms and human cancer cells.

Cancer cells are known for their remarkable uptake of glucose. They break down glucose at a rate that is two hundred times faster than average cells, a phenomenon referred to as aerobic glycolysis (the Warburg effect). This is observable in PET scans, as higher levels of radioactive glucose at specific, metabolic sites are normally indicative of either inflammation or a malignant tumor.

Fenbendazole has the ability to impede the growth of cancer cells by preventing them from accessing the sugar required for nourishment. This is done by limiting the intake of glucose and diminishing the number of GLUT transfers alongside reducing the level of the enzyme Hexokinase II. The decrease of Hexokinase II is pivotal to constricting the cancer cells because it is necessary for their survival, and it helps them flourish by producing extra sugar and heightening lactic acidosis in the outer cellular milieu.

Restarting the protein p53 also stops fuel supply to cancer cells; when it is activated again, it impedes the GLUT1 and GLUT4 transporters (known as “glucose gates”) from expressing and functioning.

Investigation into the reactivation of the p53 gene is still debatable, and further research must be done to demonstrate that fenbendazole causes this reaction.

A growing quantity of studies have shown that fenbendazole has the potential to increase the activity of the most powerful cancer-fighting protein in the human body – p53.

It is thought that an elephant has twenty different versions of the p53 gene in its DNA, whereas humans have only one. Interestingly, this is the cause of the less frequent instances of cancer in elephants compared to humans, despite having larger body size, more cells, and more potential genetic mutations.

Interestingly, it appears that cancer cells cannot form resistance to fenbendazole, a type of de-wormer medication. Unfortunately, this isn’t the case with many chemotherapy and biological therapy drugs that the cells are able to adapt to and overcome.

When cancer cells develop resistance to medications, it is mainly due to their capability to expel them via specialized drug efflux pumps known as P-glycoproteins. Fortunately, fenbendazole is not affected by these pumps, so it is unable to be expelled by the cancer cells it enters.

Therefore, tumors are not resistant to fenbendazole, keeping it effective in destroying cancer cells unlike paclitaxel, vinblastine, docetaxel, vincristine, or other chemotherapy treatments.

Fenbendazole has the capability to make cancerous tumours more responsive to radiation therapy, in the same way that drugs in the taxane family do with chemotherapy.

Fenbendazole works similarly to a moderate inhibitor of microtubules, resulting in the destruction of cancer cells.

Fenbendazole dose guide

The original protocol for cancer care is to provide free care.

Take one capsule of Fenbendazole 222 mg every day after eating a meal high in fat, 3 days in a row. After that, take no capsule for 4 days and repeat the cycle again the following week.

Take one capsule of Vitamin E 800 U/I or its equivalent each day after eating, no pause needed.

Take two capsules of Bio-Available Curcumin 600 mg with breakfast and lunch, without waiting in between.

Take about 25 milligrams of CBD oil daily before you go to bed. Use one to two drops under your tongue.

Fenbendazole is a hydrophobic molecule, meaning it is not well absorbed by the intestines. The effectiveness of this medication can be increased by having it with food or after eating a meal.

A revised protocol for cancer treatment that is complimentary: This procedure concentrates on a more robust strategy for curing cancer, taking into account consideration all available options. It emphasizes focusing on the whole person, including their mental and physical health, diet and lifestyle in addition to the specialized healthcare they receive. The approach can be tailored to the individual and may include a combination of preventive healthcare, natural treatments, medicines, therapies, and surgery. It also emphasizes the importance of building relationships with healthcare professionals who can provide targeted support and advice when needed.

Take one capsule of 222 milligrams of fenbendazole after having a fatty dinner, without any delay.

Take one capsule of Vitamin E 800 U/I on a daily basis, without any delay.

Take two Bio-Available Curcumin 600 mg capsules, one after breakfast and one after lunch, without any waiting period in between.

Take approximately 25 milligrams of CBD oil on a daily basis, most ideally before going to bed. This can be accomplished by administering one or two drops sublingually.

Fenbenlab Fenbendazole is not hazardous to individuals who do not suffer from kidney or liver illnesses.

Reducing the possibility of a cancer recurring by means of a preventive measure.

Take one capsule of fenbendazole 222 milligrams three times a week. Have it right after a high-fat meal and then don’t take it for four days. Keep repeating the same routine every week.

Take one daily dose of vitamin E 800 IU (International Units) after eating your meal without a break. This can be in the form of one capsule or some other form.

Take two capsules of Bio-Available Curcumin every day, once in the morning and then again after lunch. Each capsule contains 600 milligrams of the compound. Don’t forget to consume them after you’ve eaten.

Take 25 milligrams of CBD oil daily before you go to sleep. Place one to two drops under your tongue.

Get your tumor marker checked periodically, have your regular yearly cancer scans. After five years if cancer has not returned, lessen the amount of tests you have.

Lowering a person’s risk of getting cancer who has not had it before through preventive techniques.

Take one capsule of Fenbendazole 222 milligrams three times a week, once daily after eating a meal high in fat. Do not take the capsule for four days in a row. Continue this cycle for ten weeks and then take a break for ten more weeks. Then repeat the cycle again.

Take one capsule of vitamin E, with 800 U/I, every day after you have finished eating, without any interruption.

Take two 600-milligram capsules of Bio-Available Curcumin each day, one after breakfast and one after lunch. Do not skip any days.

Take one to two drops (approx. 25 milligrams) of CBD oil under your tongue every night before going to sleep.

The security of Fenbendazole is well-established; however, some potential side effects may be experienced.

Toxicology reports indicate that Fenbendazole, Albendazole, and similar benzimidazoles may be safe drugs.

Although there is no drug without side effects, there does not seem to be any significant negative reports regarding the intake of Fenbendazole according to scientific evidence. However, some people have anecdotally mentioned potential toxic effects.

It is possible for up to five percent of people to suffer from stomach pains or diarrhea if they take large doses of fenbendazole in one go.

Individuals with extreme kidney or liver disability will have diminished medication secretion. This means that taking fenbendazole could lead to unintended reactions since it can build up in the body. It is best to adjust the dose according to your situation.

The procedure is intended to keep the liver in top condition, so it is suggested to follow a three day on, four day off pattern.

If fenbendazole powder is used in excessive amounts for an extended period without pausing, it can cause increased enzyme levels in the liver without any symptoms, as the substance is mainly broken down in the liver. However, this effect can be reversed by taking a break for a fortnight.

This procedure was designed with the goal of keeping the liver functioning optimally. Therefore, it is recommended to follow a weekly cycle of three days where you take the medication, followed by four days when you do not take it.

Lots of people are using fenbendazole on a regimen of five days on and two days off.

It is advised to take 250 milligrams of Milk Thistle capsules or 150 milligrams of Silymarin daily to keep the liver functioning optimally. This supplement will help ensure the organ remains in a healthy state.

Studies and investigations involving fenbendazole have established that it is an effective treatment for gastrointestinal parasites.

A separate section is devoted to the scientific pre-clinical papers, in vitro research concerning anti-cancer techniques, and clinical studies Xrelated to cancer. This area provides an overview of the information collected from published reports for those who are interested in finding out more.

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